Aldose Reductase Gene Polymorphism
Kaur n vanita v.
Aldose reductase gene polymorphism. Aldose reductase c 106t gene polymorphism in type 2 diabetics with microangiopathy in iranian individuals. Is rs759853 polymorphism in promoter of aldose reductase gene a risk factor for diabetic nephropathy. Objective we screened the human aldose reductase alr gene for dna sequence variants in type 2 diabetic and nondiabetic subjects and investigated whether the. Objective aldose reductase alr is involved in diabetic microvascular damage via the polyol pathway.
A recent meta analysis found genetic variation in the alr gene. Aldose reductase ar encoded by akr1b1 is a member of nadph dependent aldo keto reductase superfamily. The c 106t polymorphism of akr1b1 is closely related to the. Present study aimed to investigate the association of aldose reductase akr1b1 gene polymorphism 106c t.
Rs759853 with diabetic retinopathy dr in type 2. Polymorphism of aldose reductase gene and susceptibility for developing diabetic retinopathy among type 2 diabetes mellitus patients thanaa mohammed juda.